Monday, February 29, 2016

CDC Flu Update: All Areas of the US are Experiencing Elevated Influenza-Like Illness Levels – Infection Control Today

According to this week’s FluView report from the Centers for Illness Manage and Prevention (CDC), flu activity continues to raise in the United States. All of 10 regions of the country are experiencing raised influenza-adore health problem levels. H1N1 viruses are many common at this time. This is the exact same H1N1 virus that emerged in 2009 to induce a pandemic. Seasonal flu vaccines have actually included the H1N1 pandemic virus due to the fact that 2010. CDC reports this season’s vaccine is offering considerable protection versus circulating viruses this season. CDC recommends an annual flu vaccine for every person 6 months of age and older. If you have actually not gotten vaccinated yet this season, you must grab vaccinated now.

For the week ending February 20, the proportion of individuals checking out their good health care provider for influenza-adore health problem (ILI) increased from 3.1% to 3.2%, which is above the national baseline (2.1%). All of 10 regions reported ILI at or above their region-personal baseline levels. One method that CDC measures the length of the influenza season is the lot of consecutive weeks throughout which ILI is at or above the national baseline. ILI has actually been at or above the national baseline for 6 consecutive weeks so much this season. For the last 13 seasons, the standard duration of a flu season by this measure has actually been 13 weeks, along with a range from 1 week to twenty weeks.

Puerto Rico and 6 states (Arizona, California, Brand-new Mexico, North Carolina, Texas, and Utah) endured higher ILI activity. Brand-new York City and 6 states (Arkansas, Connecticut, Florida, Illinois, Brand-new Jersey, and Oregon) endured moderate ILI activity. 13 states (Alabama, Georgia, Hawaii, Kansas, Kentucky, Louisiana, Massachusetts, Michigan, Minnesota, Mississippi, Oklahoma, South Carolina, and Virginia) endured reasonable ILI activity. 24 states endured minimal ILI activity. The District of Columbia and one Claim (Colorado) did not have actually sufficient data to calculate a task level. ILI activity data indicate the quantity of flu-adore health problem that is occurring in each state.

Widespread flu activity was reported by Guam, Puerto Rico and 21 states (Arizona, California, Connecticut, Iowa, Kentucky, Maryland, Massachusetts, Michigan, Minnesota, Nevada, Brand-new Hampshire, Brand-new Jersey, Brand-new Mexico, Brand-new York, North Dakota, Pennsylvania, Texas, Utah, Vermont, Virginia, and Washington). Local flu activity was reported by 18 states (Alabama, Florida, Georgia, Hawaii, Idaho, Indiana, Kansas, Maine, Montana, Nebraska, North Carolina, Ohio, Oklahoma, Oregon, Rhode Island, South Dakota, Tennessee, and Wyoming). The District of Columbia and 10 states (Alaska, Arkansas, Colorado, Delaware, Illinois, Louisiana, Mississippi, Missouri, South Carolina, and Wisconsin) reported neighborhood influenza activity. The U.S. Virgin Islands and 1 Claim (West Virginia) reported sporadic influenza activity. Geographic spread data reveal exactly how several spots within a Claim or territory are checking out flu activity.

Since October 1, 2015, 1,594 laboratory-confirmed influenza-associated hospitalizations have actually been reported through FluSurv-NET, a population-based surveillance network for laboratory-confirmed influenza-associated hospitalizations. This translates to a cumulative total price of 5.8 hospitalizations per 100,000 individuals in the United States. This is substantially lesser compared to the hospitalization price at this time last season (54.4 per 100,000). Much more data on hospitalization rates, including hospitalization paces throughout various other influenza seasons, are offered at http://ift.tt/1GhvmFp and http://ift.tt/1T8B5aJ. ◦The highest hospitalization paces are among individuals 65 years and older (16.7 per 100,000), followed by youngsters younger compared to 5 years (8.6 per 100,000), and adults 50-64 years (7.4 per 100,000). throughout many seasons, youngsters younger compared to 5 years and adults 65 years and older have actually the highest hospitalization rates. FluSurv-NET hospitalization data are collected from 13 states and represent about 8.5% of the total U.S. population. The lot of hospitalizations reported does not reflect the real total lot of influenza-associated hospitalizations in the United States.

The proportion of deaths attributed to pneumonia and influenza (P&I) was listed here the system-personal epidemic threshold in the two the NCHS Mortality Surveillance System and the 122 Cities Mortality Reporting System. One influenza-associated pediatric death was reported to CDC throughout the week ending February 20. ◦This death was associated along with an influenza B virus and taken place throughout week 7 (the week ending February 20, 2016). A total of 14 influenza-associated pediatric deaths have actually been reported throughout the 2015-2016 season.

Nationally, the percentage of respiratory specimens testing favorable for influenza viruses in clinical laboratories throughout the week ending February twenty was 13.8%. For the current 3 weeks, the Local percentage of respiratory specimens testing favorable for influenza viruses in clinical laboratories ranged from 4.3% to 16.1%. ◦throughout the week ending February 20, of the 2,599 influenza-favorable examinations reported to CDC by clinical laboratories, 1,978 (76.1%) were influenza A viruses and 621 (23.9%) were influenza B viruses.

The many regularly identified influenza virus kind reported by public good health laboratories throughout the week ending February twenty was influenza A viruses, along with influenza A (H1N1)pdm09 viruses predominating. ◦throughout the week ending February 20, 694 (77.8%) of the 892 influenza-favorable examinations reported to CDC by public good health laboratories were influenza A viruses and 198 (22.2%) were influenza B viruses. Of the 647 influenza A viruses that were subtyped, 83 (12.8%) were H3 viruses and 564 (87.2%) were (H1N1)pdm09 viruses. Cumulatively from October 4, 2015-February 20, 2016, influenza A (H1N1)pdm09 viruses were predominant in All of four age teams (0-4 years age group (67.8%), 5-24 years age group (45.6%),  25-64 years age group (70.1%), and in ages 65 years and older (42.4%).

CDC has actually characterized 660 specimens (271 influenza A (H1N1)pdm09, 242 influenza A (H3N2) and 147 influenza B viruses) collected in the U.S. due to the fact that October 1, 2015. ◦All of 271 (100%) influenza A (H1N1)pdm09 viruses were antigenically characterized as just like A/California/7/2009, the influenza A (H1N1) component of the 2015-2016 Northern Hemisphere vaccine. All of 242 H3N2 viruses were genetically sequenced and All of viruses belonged to genetic teams for which a majority of viruses antigenically characterized were just like cell-propagated A/Switzerland/9715293/2013, the influenza A (H3N2) component of the 2015-2016 Northern Hemisphere vaccine. A subset of 109 H3N2 viruses additionally were antigenically characterized; 102 of 109 (93.6%) H3N2 viruses were just like A/Switzerland/9715293/2013 by HI testing or neutralization testing. All of 88 (100%) of the B/Yamagata-lineage viruses were antigenically characterized as just like B/Phuket/3073/2013, which is included in the two the 2015–16 Northern Hemisphere trivalent and quadrivalent vaccines. Fifty-eight of 59 (98.3%) of the B/Victoria-lineage viruses were antigenically characterized as just like B/Brisbane/60/2008, which is included in the 2015-16 Northern Hemisphere quadrivalent vaccine.

Since October 1, 2015, CDC has actually tested 452 influenza A (H1N1)pdm09, 307 influenza A (H3N2), and 269 influenza B viruses for resistance to the neuraminidase inhibitors antiviral drugs. While the vast majority of the viruses that have actually been tested are sensitive to oseltamivir, zanamivir, and peramivir, so much this season, 2 (0.4%) influenza A (H1N1)pdm09 viruses have actually showed resistance to oseltamivir and peramivir (yet the two were sensitive to zanamivir).

Source: CDC



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